王晓莹,赵青,陈大春.精神分裂症患者肠道菌群失调对认知功能受损的影响[J].四川精神卫生杂志,2022,35(3):292-296.Wang Xiaoying,Zhao Qing,Chen Dachun,Effects of gut microbiome imbalance on impaired cognitive function in patients with schizophrenia[J].SICHUAN MENTAL HEALTH,2022,35(3):292-296
精神分裂症患者肠道菌群失调对认知功能受损的影响
Effects of gut microbiome imbalance on impaired cognitive function in patients with schizophrenia
投稿时间:2021-12-01  
DOI:10.11886/scjsws20211201001
中文关键词:  精神分裂症  肠道菌群  认知功能  菌群失调
英文关键词:Schizophrenia  Gut microbiome  Cognitive function  Microbiome imbalance
基金项目:
作者单位邮编
王晓莹 北京大学医学部北京 100191 100191
赵青 北京大学医学部北京 100191 100191
陈大春 北京大学医学部北京 100191
北京大学回龙观临床医学院·北京回龙观医院北京 100096 
100096
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中文摘要:
      本文目的是综述精神分裂症患者肠道菌群失调对认知功能受损的影响,为改善精神分裂症患者认知功能受损情况的新方法提供参考。精神分裂症患者的认知功能受损普遍存在,是阻碍其重返社会的重要原因之一。随着肠道菌群-肠-脑轴概念的提出,许多研究者发现精神分裂症患者肠道菌群失调与认知功能受损存在一定联系,本文阐述并总结既往研究中发现的此种联系,以期为改善精神分裂症患者认知功能受损情况提供参考。
英文摘要:
      The objective of this study is to elucidate the effects of gut microbiome imbalance on impaired cognitive function in schizophrenia patients, and to propose a new approach to improve cognitive impairment in schizophrenia patients. The cognitive impairment of schizophrenic patients is one of the major barriers that hinder patient social reintegration. With the emergence of microbiome-gut-brain axis, many researchers have found that there is a certain relationship between gut microbiome imbalance and impaired cognitive function in schizophrenia patients, so this paper reviews and summarizes such relationship found in previous studies, with a view to informing the exploration of new ways to improve cognitive impairment in schizophrenia patients.
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