洪家坤,孙艳兵,刘小兵.齐拉西酮致药物性皮炎1例[J].四川精神卫生杂志,2022,35(4):370-372.Hong Jiakun,Sun Yanbing,Liu Xiaobing,Drug eruption caused by ziprasidone: a case report[J].SICHUAN MENTAL HEALTH,2022,35(4):370-372
齐拉西酮致药物性皮炎1例
Drug eruption caused by ziprasidone: a case report
投稿时间:2021-11-24  
DOI:10.11886/scjsws20211124001
中文关键词:  齐拉西酮  药物性皮炎  不良反应
英文关键词:Ziprasidone  Drug eruption  Adverse reactions
基金项目:
作者单位邮编
洪家坤 中国人民解放军联勤保障部队第九二三医院贵港医疗区广西 贵港 537100 537100
孙艳兵 中国人民解放军联勤保障部队第九二三医院贵港医疗区广西 贵港 537100 537100
刘小兵 中国人民解放军联勤保障部队第九二三医院贵港医疗区广西 贵港 537100 537100
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中文摘要:
      本文报告了一例服用齐拉西酮致药物性皮炎的男性首发精神分裂症患者。患者接受单一齐拉西酮治疗,服药后病情改善,但出现药物性皮炎,伴发热、白细胞升高。未停用齐拉西酮时,即使给予抗过敏治疗,皮疹并未消退;停用齐拉西酮并给予抗过敏治疗后,皮疹消退。此案例提示,在使用齐拉西酮时,应重视个体的过敏史,关注皮肤方面的不良反应并及时干预,避免发展为重症药疹。
英文摘要:
      This paper reported a case of drug eruption in a male patient with first-episode schizophrenia. The patient received ziprasidone monotherapy, and experienced post-treatment remission of schizophrenic symptoms, while accompanied by drug eruption with fever and elevated white blood cell count. Even with antiallergic treatment, the eruption did not subside without discontinuation of ziprasidone, whereas the eruption resolved after discontinuation of ziprasidone. This case suggested that individual allergy history should be taken into account during the use of ziprasidone, and timely intervention of adverse skin reactions was essential to prevent the development of severe drug eruption.
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