| YU Xiang -fen,MA Ai - hua,DONG Jun - ling,Relationship between metabolic syndrome and hepatitis B virus infection in patients with schizophrenia[J].SICHUAN MENTAL HEALTH,2014,27(1):33-37 |
| Relationship between metabolic syndrome and hepatitis B virus infection in patients with schizophrenia |
DOI： |
| English keywords:Schizophrenia Hepatitis B virus Metabolic syndrome |
| Fund projects:临沂市科技发展计划项目（201313061） |
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| English abstract: |
| Objective To explore the relationship between metabolic syndrome （MS） and hepatitis B virus （HBV） infection in patients with schizophrenia. Methods 600 inpatients with schizophrenia were recruited in this study. Basic information such as the de- mographic information , medical data of the patients were recorded, physical parameters such as height, body weight, waist circumfer- ence, blood pressure were collected. Blood samples were also collected to detect the status of HBV infection and biochemical parame- ters, such as fasting blood sugar, serum total protein, albumin, globulin, creatinine, uric acid, triglyeeride, total cholesterol, high - density lipoprotein （ HDL - C ）, low - density lipoprotein （ LDL - C ）. The MS was diagnosed according to criteria defined by Preventive Guideline of Dyslipidemia for Chinese Adults. Results The prevalence of HBsAg infection was 11.83% in inpatients with schizophre- nia. Frequency of positive HBsAg infection in MS group was 19.78 % , and was higher than the frequency （ 1 0.41% ） in non - MS group （P = 0. 018）. The crude OR between MS and HBV infection was 2. 121,95% confidence interval（CI） was 1. 342 to 3. 324. Adjusted OR was 2. 068,95% CI was 1. 322 to 3. 228 after age and gender were adjusted. Conclusion HBV infection might increase the prev- alence of MS in patients with schizophrenia. |
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