Xiao Xuman,Huang Wei,Huang Shiqing,Chen Hui,Zhu Cuixing,Lin Xueping,Li Xiaoling,Effect of family intervention assisted lithium carbonate in the treatment of convalescent bipolar disorder[J].SICHUAN MENTAL HEALTH,2019,32(6):514-517
Effect of family intervention assisted lithium carbonate in the treatment of convalescent bipolar disorder
DOI:10.11886/scjsws20190810002
English keywords:Family intervention  Lithium carbonate  Bipolar disorder  Anxiety  Depression  Quality of life
Fund projects:佛山市医学类科技攻关项目 2017AB002211 佛山市医学类科技攻关项目(2017AB002211)
Author NameAffiliation
Xiao Xuman The Third People's Hospital of Foshan, Foshan 528041, China 
Huang Wei The Third People's Hospital of Foshan, Foshan 528041, China 
Huang Shiqing The Third People's Hospital of Foshan, Foshan 528041, China 
Chen Hui The Third People's Hospital of Foshan, Foshan 528041, China 
Zhu Cuixing The Third People's Hospital of Foshan, Foshan 528041, China 
Lin Xueping The Third People's Hospital of Foshan, Foshan 528041, China 
Li Xiaoling The Third People's Hospital of Foshan, Foshan 528041, China 
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English abstract:
      Objective To explore the efficacy of family intervention assisted lithium carbonate in the treatment of bipolar disorder patients at convalescent phase, and to provide references for related treatment. Methods Based on diagnostic criteria of Diagnostic and Statistical Manual of Mental Disorders, fifth edition (DSM-5), a total of 68 bipolar disorder patients with stable condition and continuous lithium carbonate treatment who were hospitalized in Third People's Hospital of Foshan from January to December 2018 and discharged for two months were enrolled. The selected individuals were divided into control group and study group according to the random number table method, 34 cases each. Both groups received lithium carbonate treatment, based on this, the study group applied family intervention once every two weeks; treatments in both groups lasted for 4 months. Then the anxiety and depression symptoms, as well as the quality of life of patients were assessed by Self-rating Anxiety Scale (SAS), Self-rating Depression Scale (SDS), and the World Health Organization Quality of Life-Brief Version (WHOQOL-BREF). Results After intervention, the total scores of SAS and SDS in the study group were lower than those in the control group [(47.21±2.79) vs. (52.79±2.42), (53.32±2.43) vs. (56.41±3.49), t=8.813, 4.231, P<0.01]. The scores of physiological field, psychological field, social relations and the total scores of WHOQOL-BREF in the study group were all higher than those in the control group [(5.62±0.63) vs. (4.29±0.35), (12.42±4.24) vs. (5.38±1.34), (3.46±0.34) vs. (1.38±0.53), (39.14±11.21) vs. (29.19±4.42), t=4.815~19.260, P<0.01]. Conclusion Compared with lithium carbonate treatment, its combination with family intervention for bipolar disorder patients at convalescent phase has better clinical efficacy, and the quality of life of patients is also better.
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