Deng Hongjiang,Zhang Lan,Oculogyric crisis caused by clozapine: a case report[J].SICHUAN MENTAL HEALTH,2022,35(5):467-470
Oculogyric crisis caused by clozapine: a case report
DOI:10.11886/scjsws20220614001
English keywords:Schizophrenia  Clozapine  Dystonia  Oculogyric crisis  Therapeutic drug monitoring
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Author NameAffiliationPostcode
Deng Hongjiang West China Hospital of Sichuan University Chengdu 610040 China 610040
Zhang Lan* West China Hospital of Sichuan University Chengdu 610040 China 610040
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English abstract:
      This paper reported a case of a 14-year-old female patient with schizophrenia of more than 2 years who had poor efficacy on atypical antipsychotics such as aripiprazole, risperidone and olanzapine, and who developed acute dystonia adverse effects during administration. Subsequently, the treatment was changed to clozapine therapy, and during this treatment, the patient's psychotic symptoms improved, but developed salivation and adverse effects such as clozapine-induced oculogyric crisis, slurred speech and dysphagia. This paper discussed this case with a view to providing a reference for clinicians in the recognition and management of oculogyric crisis caused by clozapine.
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