Tao Weiqun,Ye Xiaoying,Ren Li'na,Xie Xinhui,Deng Haihua,Chen Baixin,Li Yun,Analysis of risk factors for delirium in critically ill patients in a psychiatric hospital: a retrospective study[J].SICHUAN MENTAL HEALTH,2023,36(3):242-247
Analysis of risk factors for delirium in critically ill patients in a psychiatric hospital: a retrospective study
DOI:10.11886/scjsws202320230217002
English keywords:Psychiatric hospital  Critically ill patients  Delirium  Risk factors  Retrospective study
Fund projects:广东省高水平临床重点专科(深圳市配套建设经费)资助(项目编号:SZGSP013)
Author NameAffiliationPostcode
Tao Weiqun Shantou University Medical College Shantou 515041 China
Shenzhen Mental Health Center/Shenzhen Kangning Hospital Shenzhen 518020 China 
518020
Ye Xiaoying Shantou University Medical College Shantou 515041 China
Shenzhen Mental Health Center/Shenzhen Kangning Hospital Shenzhen 518020 China 
518020
Ren Li'na Shenzhen Mental Health Center/Shenzhen Kangning Hospital Shenzhen 518020 China 518020
Xie Xinhui Renmin Hospital of Wuhan University Wuhan 430060 China 430060
Deng Haihua Shenzhen Baoan District Fuyong People's Hospital Shenzhen 518103 China 518103
Chen Baixin Shantou University Mental Health Center Shantou 515065 China 515065
Li Yun* Shantou University Medical College Shantou 515041 China
Shantou University Mental Health Center Shantou 515065 China 
515065
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English abstract:
      Background The incidence of delirium in critically ill psychiatric patients is high, and there are many factors affecting delirium occurrence. At present, epidemiological studies on delirium among critically ill patients in psychiatric hospitals are limited.Objective To explore the risk factors for delirium in critically ill patients in a psychiatric hospital, so as to guide the clinical management of delirium in psychiatric hospitals.Methods This retrospective study included 427 critically ill patients who were admitted to Shenzhen Kangning Hospital from January 1, 2019 to May 31, 2021. The delirium situation, gender, age, pre-admission course of illness (duration from the onset of acute mental state changes to in-patient registration at a psychiatric hospital), history of mental illness, history of cognitive dysfunction, history of using psychoactive substances, history of using sedative and hypnotic drugs, number of combined chronic diseases, number of combined drugs and type of disease were examined as potential risk factors for delirium. Single Logistic regression was used to analyze the potential risk factors for delirium, and the potential risk factors were incorporated into the multi-factor Logistic regression analysis model so as to gradually screen out the risk factors for delirium in critically ill psychiatric patients.Results Delirium was present in 33.49% (143/427) of critically ill patients. Multi-factor Logistic regression analysis demonstrated that the presence of delirium was associated with mental and behavioral disorders caused by psychoactive substances (OR=8.949, P<0.01), absent history of mental illness (OR=4.202, P<0.01), number of combined chronic diseases (OR=1.249, P<0.01), age (OR=1.031, P<0.01) and pre-admission course of illness (OR=0.942, P<0.01) .Conclusion Delirium was present in nearly 1/3 critically ill patients in the psychiatric hospital. The risk factors for delirium included short course of illness before admission, age, more combined chronic diseases, absent history of mental illness, mental and behavioral disorders caused by psychoactive substances. [Funded by Shenzhen Fund for Guangdong Provincial High-level Clinical Key Specialties (number, SZGSP013)]
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