| Chen Ping,Wang Lu,Shen Xinhua,Progress based on the clinical translation of the anxiolytic effects of oxytocin[J].SICHUAN MENTAL HEALTH,2023,36(3):271-276 |
| Progress based on the clinical translation of the anxiolytic effects of oxytocin |
DOI：10.11886/scjsws20221227001 |
| English keywords:Oxytocin Anxiety Clinical translation |
| Fund projects:浙江省卫生健康科技计划（临床研究应用项目）（项目名称：鼻腔喷雾催产素后静息态脑功能变化预测广泛性焦虑障碍急性期疗效的研究，项目编号：2022KY367） |
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| The etiology and pathogenesis of anxiety disorders were still unknown with limited progress in treatment， and had a low cure rate and a high relapse rate. Oxytocin has attracted attention in recent years due to its anxiolytic effect， especially validated in animal experiments， but there are few studies in humans. Therefore， the purpose of this paper is to illustrate the pathological mechanism of anxiety through review researches on oxytocin and anxiety in recent years. Anxiety disorder is one of the most common mental disorder， and the imbalance of neurotransmitters is one of the pathogenesis. As a common neurotransmitter in the brain， oxytocin participated in the process of anxiety regulation. The purpose of this article is to summarize the research related to oxytocin to explore its possible mechanism of regulating anxiety， and to provide new ideas for diagnosis and treatment of anxiety disorders in combination with the clinical findings. ［Funded by Zhejiang Health Science and Technology Plan （number， 2022KY367）］. |
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