| Li Bin,Jiang Jiaxin,Li Hailong,Zheng Zhong,Huang Xiaoqi,Relationship between intolerance of uncertainty and obsessive-compulsive disorder pathology and neurobiological mechanisms[J].SICHUAN MENTAL HEALTH,2025,(3):193-197 |
| Relationship between intolerance of uncertainty and obsessive-compulsive disorder pathology and neurobiological mechanisms |
DOI：10.11886/scjsws20240604002 |
| English keywords:Obsessive-compulsive disorder Intolerance of uncertainty Magnetic resonance imaging Psychopathology Neural mechanisms |
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| Author Name | Affiliation | Postcode | | Li Bin* | Mental Health Center, West China Hospital, Sichuan University, Sichuan, Chengdu 610041, China | 610041 | | Jiang Jiaxin | Mental Health Center, West China Hospital, Sichuan University, Sichuan, Chengdu 610041, China
Chengdu Eighth People's Hospital, Chengdu 610081, China | 610081 | | Li Hailong | Huaxi MR Research Center , Institution of Radiology and Medical Imaging, West China Hospital, Sichuan University, Chengdu 610041, China
Functional and Molecular Imaging Key Laboratory of Sichuan Province, West China Hospital of Sichuan University, Chengdu 610041, China | 610041 | | Zheng Zhong | Center for Neurological Function Test and Neuromodulation, West China Xiamen Hospital, Sichuan University, Xiamen 361021, China | 361021 | | Huang Xiaoqi | Huaxi MR Research Center , Institution of Radiology and Medical Imaging, West China Hospital, Sichuan University, Chengdu 610041, China
Functional and Molecular Imaging Key Laboratory of Sichuan Province, West China Hospital of Sichuan University, Chengdu 610041, China | 610041 |
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| English abstract: |
| Obsessive-compulsive disorder （OCD） is a highly disabling mental disorder that impairs patients' social function and quality of life， and impose a substantial economic burden. Intolerance of uncertainty （IU） refers to a cognitive bias in perceiving， interpreting and responding to uncertain situations or events. IU is closely associated with the cognitive patterns of OCD patients. Based on magnetic resonance imaging （MRI）， this paper discusses the research progress of the relationship between IU and psychopathological characteristics of OCD， and put forward the research direction， aims to provide evidence-based references for the development of optimized therapeutic interventions for OCD. |
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