| Miao Shipan,Li Jun,Wang Qianqian,Song Suqi,Zhang Kai,Impact of smartphone games on cognitive function in patients with chronic schizophrenia and gender differences[J].SICHUAN MENTAL HEALTH,2026,39(1):44-49 |
| Impact of smartphone games on cognitive function in patients with chronic schizophrenia and gender differences |
DOI：10.11886/scjsws20250719001 |
| English keywords:Schizophrenia Smartphone games Cognitive function Gender differences Immediate memory |
| Fund projects:安徽省教育厅高校优秀青年人才支持计划项目（项目编号：gxyqZD2022022） |
| Author Name | Affiliation | Postcode | | Miao Shipan | 1Chaohu Hospital Affiliated to Anhui Medical University, Hefei 238000, China | 238000 | | Li Jun | 1Chaohu Hospital Affiliated to Anhui Medical University, Hefei 238000, China | 238000 | | Wang Qianqian | 2School of Mental Health and Psychological Sciences, Anhui Medical University, Hefei 238000, China | 238000 | | Song Suqi | 1Chaohu Hospital Affiliated to Anhui Medical University, Hefei 238000, China | 238000 | | Zhang Kai* | 1Chaohu Hospital Affiliated to Anhui Medical University, Hefei 238000, China
3Anhui Provinvial Mental Health Center, Hefei 238000, China | 238000 |
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| Background Patients with chronic schizophrenia often suffer from cognitive impairment. Traditional cognitive rehabilitation training has problems such as a single form and poor compliance， making it urgent to develop new cognitive intervention methods.Objective To explore the intervention effect of smartphone games on the cognitive function of patients with chronic schizophrenia， and to analyze the differences in cognitive function improvement between patients of different genders， in order to provide references for the cognitive function intervention of these patients.Methods This study was a prospective cohort study. A total of 30 patients who were hospitalized in the Psychiatry Department of Chaohu Hospital Affiliated to Anhui Medical University from March to October 2021， met the diagnostic criteria for schizophrenia as defined in the International Classification of Diseases， tenth edition （ICD-10）， and had a disease duration of above 5 years， were selected as the research subjects. All patients received smartphone game intervention for 12 weeks， 5 times a week， each session lasting 1 hour， in addition to conventional antipsychotic drug treatment. At the baseline and at 3， 6， 9， and 12 weeks of the intervention， the cognitive function was evaluated using the Repeatable Battery for the Assessment of Neuropsychological Status （RBANS）， the Positive and Negative Syndrome Scale （PANSS） was used to assess mental symptoms， and the Problematic Mobile Gaming Questionnaire （PMGQ） was used to assess addiction symptoms.Results A total of 26 patients （86.67%） completed the study， including 13 females and 13 males. The time effects， group effects， and interaction effect between time and group for the immediate memory factor score of RBANS in the female group and the male group were all statistically significant （F=36.682， 5.712， 3.090， P<0.05 or 0.01）， and the time effects and group effects for the verbal and delayed memory factors as well as the total score in both groups were also statistically significant （F=3.841， 6.149， 15.372， P<0.05 or 0.01）. The time effects and group effects of the total score of PANSS in both groups had no statistical significance （F=2.041， 0.623， P>0.05 for both）， and the interaction effect between time and group was statistically significant （F=5.728， P<0.01）. The time effects， group effects， and interaction effect of the total score of PMGQ in both groups were all without statistical significance （F=2.672， 0.166， 0.642， P>0.05 for both）.Conclusion Smartphone game intervention may help improve the cognitive function of patients with chronic schizophrenia （especially immediate memory， verbal function， and delayed memory）， and the benefits are greater for female patients. The smartphone game intervention did not induce game addiction， but no significant improvement in psychotic symptoms was observed. ［Funded by Excellent Young Talents Support Program of Anhui Provincial Department of Education （number， gxyqZD2022022）； www.chictr.org.cn number， ChiCTR2100044113］ |
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