Zhou Nvshi,Peng Xumei,Cao Zhiyue,Liu Chengcheng,Yao Jing,Correlation between objective short sleep duration and dyslipidemia in patients with chronic insomnia disorder[J].SICHUAN MENTAL HEALTH,2026,39(1):58-62
Correlation between objective short sleep duration and dyslipidemia in patients with chronic insomnia disorder
DOI:10.11886/scjsws20250304001
English keywords:Chronic insomnia disorder  Objective sleep duration  Dyslipidemia  Lipid profile
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Author NameAffiliationPostcode
Zhou Nvshi 1Clinical Medical College of North Sichuan Medical College, Nanchong 637000, China
2Sichuan Mental Health Center·The Third Hospital of Mianyang, Mianyang 621000, China 
621000
Peng Xumei 1Clinical Medical College of North Sichuan Medical College, Nanchong 637000, China
2Sichuan Mental Health Center·The Third Hospital of Mianyang, Mianyang 621000, China 
621000
Cao Zhiyue 1Clinical Medical College of North Sichuan Medical College, Nanchong 637000, China
2Sichuan Mental Health Center·The Third Hospital of Mianyang, Mianyang 621000, China 
621000
Liu Chengcheng 1Clinical Medical College of North Sichuan Medical College, Nanchong 637000, China
2Sichuan Mental Health Center·The Third Hospital of Mianyang, Mianyang 621000, China 
621000
Yao Jing* 2Sichuan Mental Health Center·The Third Hospital of Mianyang, Mianyang 621000, China 621000
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English abstract:
      Background Chronic insomnia disorder has become a significant public health issue, and it may be associated with dyslipidemia. Previous studies on dyslipidemia in patients with chronic insomnia disorder have mainly focused on exploring the relationship between subjective short sleep duration and dyslipidemia, while there have been limited studies on the relationship between objective short sleep duration and dyslipidemia.Objective To explore the relationship between objective short sleep duration and dyslipidemia in patients with chronic insomnia disorder, in order to provide references for the prevention and intervention of dyslipidemia in this population.Methods A total of 103 patients who were hospitalized at The Third Hospital of Mianyang from August 2022 to November 2023 and met the diagnostic criteria for chronic insomnia disorder as defined in the International Classification of Sleep Disorder, third edition (ICSD-3) were retrospectively collected. The objective sleep duration of the patients was obtained through polysomnography. The patients were divided into two groups based on their objective sleep duration: the group with objective sleep duration ≥ 7 hours (n=71) and the group with objective sleep duration < 7 hours (n=32). Binary Logistic regression analysis was used to explore the impact of objective sleep duration < 7 hours on dyslipidemia.Results Among 103 patients with chronic insomnia disorder, 59 cases (57.28%) were identified with dyslipidemia. The comparison of dyslipidemia conditions between the group with objective sleep duration ≥ 7 hours and the group with objective sleep duration < 7 hours showed a statistically significant difference (χ2=5.956, P<0.05). Compared with the group with objective sleep duration ≥7 hours, the group with objective sleep duration < 7 hours exhibited significantly lower high-density lipoprotein cholesterol levels, and reduced sleep efficiency (t=-2.003, -5.482, P<0.05 or 0.01). Binary Logistic regression analysis results showed that the risk of abnormal blood lipids in patients with chronic insomnia disorder with objective sleep duration < 7 hours was 3.128 times higher than that of patients with objective sleep duration ≥ 7 hours (OR=3.128, 95% CI: 1.139–8.588).Conclusion Objective short sleep duration may be a risk factor for dyslipidemia in patients with chronic insomnia disorder.
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