| Shao Yuan,Wang Jian,Liang Wei,Zhang Yingli,Hou Gangqiang,Li Xia,Xing Yi,Wang Lu,Tang Shi,Wang Yongjun,Expert consensus on precise intervention with repetitive transcranial magnetic stimulation for sleep disorders in the elderly[J].SICHUAN MENTAL HEALTH,2026,(2):97-105 |
| Expert consensus on precise intervention with repetitive transcranial magnetic stimulation for sleep disorders in the elderly |
DOI：10.11886/scjsws20260306001 |
| English keywords:The elderly Sleep disorders Repetitive transcranial magnetic stimulation Depression disorder Mild cognitive impairment Alzheimer's disease |
| Fund projects:国家重点研发计划（项目名称：衰老过程心理-睡眠-认知相互作用机理及干预研究，项目编号：2023YFC3603200）；深圳市科技创新局基础研究面上项目（项目名称：老年睡眠障碍的时空图神经网络（STGNN）机制研究，项目编号：JCYJ20240813112859008；项目名称：生物节律介导的脑类淋巴系统功能紊乱在抑郁症发病机制中的研究，项目编号：JCYJ20240813112900002）；市康宁医院院级科研项目-青年项目（项目名称：光生物节律调控在AD治疗中的作用及其机制研究，项目编号：KN2023A004） |
| Author Name | Affiliation | Postcode | | Shao Yuan | 1Shenzhen Kangning Hospital, Shenzhen Mental Health Center, Shenzhen 518118, China | 518118 | | Wang Jian | 1Shenzhen Kangning Hospital, Shenzhen Mental Health Center, Shenzhen 518118, China | 518118 | | Liang Wei | 1Shenzhen Kangning Hospital, Shenzhen Mental Health Center, Shenzhen 518118, China | 518118 | | Zhang Yingli | 1Shenzhen Kangning Hospital, Shenzhen Mental Health Center, Shenzhen 518118, China | 518118 | | Hou Gangqiang | 1Shenzhen Kangning Hospital, Shenzhen Mental Health Center, Shenzhen 518118, China | 518118 | | Li Xia | 2Mental Health Center, Shanghai Jiao Tong University School of Medicine, Shanghai 200030, China | 200030 | | Xing Yi | 3Xuanwu Hospital, Capital Medical University, Beijing 100053, China | 100053 | | Wang Lu | 4School of Basic Medical Science, Fudan University, Shanghai 200032, China | 200032 | | Tang Shi | 5Shandong Provincial Hospital, Ji'nan 250021, China | 250021 | | Wang Yongjun* | 1Shenzhen Kangning Hospital, Shenzhen Mental Health Center, Shenzhen 518118, China | 518118 |
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| In recent years， repetitive transcranial magnetic stimulation （rTMS） has garnered significant attention as a therapeutic approach for sleep disorders in the elderly. However， the prevailing rTMS protocols are predominantly developed based on normative neurophysiological data derived from young adults and fail to incorporate individualized parameters tailored to the brain characteristics of the elderly. To address this gap， the consensus development group synthesized the latest evidence from 2010 to 2025 and established a standardized rTMS protocol specifically for elderly patients with sleep disorders. Adhering to the Appraisal of Guidelines for Research and Evaluation II （AGREE II） framework， systematically screened randomized controlled trials （RCTs） and systematic reviews regarding rTMS in the treatment of sleep disorders across various conditions. Meanwhile， the Grading of Recommendations Assessment， Development and Evaluation （GRADE） system was employed to rigorously grade the quality of evidence and the strength of recommendations. This consensus guideline delineates precise rTMS protocols for the management of sleep disorders in the elderly， highlights the adjustment of stimulation intensity according to scalp-cortex distance recommends either MRI-guided neuronavigation or the Beam F3/F4 heuristic approach for accurate target localization， thereby providing precise rTMS intervention protocol for sleep disorders in the elderly， aiming to enhance clinical efficacy while ensuring treatment safety. ［Funded by National Key Research and Development Program （number， 2023YFC3603200）； General Program of Shenzhen Science and Technology Innovation Commission （number， JCYJ20240813112859008， JCYJ20240813112900002）； Youth Program of Shenzhen Kangning Hospital （number， KN2023A004）； www.guidelines-registry.cn number， PREPARE-2026CN530］ |
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