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| Relationship between mitochondrial dynamics, neuroinflammation and schizophrenia |
DOI： |
| English keywords:Schizophrenia Immune inflammation Mitochondria Microglia |
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| The purpose of this paper is to review the research progress of mitochondrial dysfunction and microglial inflammation in the pathophysiology of schizophrenia and to provide reference for the pathogenesis of schizophrenia. Schizophrenia is a serious mental disease. Immune inflammatory pathway is considered to be one of the main pathogenesis of schizophrenia, which is characterized by the activation of microglia and the increase of inflammatory factors in the brain. However, the biological mechanism of immune disorder in schizophrenia has not been fully elucidated. There is increasing evidence that mitochondrial dysfunction may play a key role in the pathogenesis of schizophrenia. This article reviews the research progress of mitochondrial function and microglial inflammation in the pathophysiology of schizophrenia. |
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