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| 老年期抑郁障碍的临床诊治 |
| Clinical diagnosis and treatment of late-life depression |
| 投稿时间：2024-03-27 修订日期：2024-03-27 |
| DOI： |
| 中文关键词: 老年期抑郁障碍 共病 药物治疗 认知功能 |
| 英文关键词:Late-life depression Comorbidity Drug therapy Cognitive function |
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| 中文摘要: |
| 【】随着老龄化进程的加快和社会生活方式的转变,老年期抑郁障碍(LLD)的患病率有逐年增加的趋势。作为最常见的老年期精神障碍,LLD严重影响患者的生活质量,并给家庭和社会带来沉重负担,甚至可能威胁老年患者的生命安全。LLD的发病机制尚不明确,可能是生物、社会和心理多方面因素共同作用所致。由于老年群体的机体功能衰退、共病躯体疾病较多,故对LLD患者的诊治与处理年轻的成年抑郁障碍患者会有所不同。本文对LLD相关的流行病学特征、临床评估和诊断、共病情况以及治疗与干预等方面进行了简要梳理,着重介绍了LLD的药物治疗,以期为临床对LLD的优化诊疗提供参考。 |
| 英文摘要: |
| 【】With the acceleration of the aging process and the change of social life style, the prevalence of late-life depression(LLD) in the elderly is increasing year by year. As the most common mental disorder in the elderly, LLD seriously affects the quality of life of patients, and brings a heavy burden to the family and society, and may even threaten the life safety of elderly patients. The pathogenesis of LLD is still unclear, which may be caused by the combined effects of biological, social and psychological factors. Because of the decline of body function and more comorbid physical diseases in the elderly population, the diagnosis and treatment of LLD patients may be different from that of young adult patients with depression, and more attention should be paid to the characteristics of LLD patients in clinical treatment. This paper reviews the epidemiological characteristics, clinical evaluation and diagnosis, comorbidity, treatment and intervention of LLD, and focuses on the selection of therapeutic drugs and adverse reactions, in order to provide reference for better diagnosis and treatment of LLD and improve the prognosis of patients. |
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